Hybrid Deep Learning and Neuro-Fuzzy Approach for COVID-19 Diagnosis Using CT Scan Imaging: Integration of CNN, ANFIS, and PCA

Mohamed H Ghaleb Abdkhaleq
International Journal of Computational and Electronic Aspects in Engineering
Volume 6: Issue 2, June 2025, pp 81-88


Author's Information
Mohamed H Ghaleb Abdkhaleq 1 
Corresponding Author
1College of Computer Science and Information Technology, Wasit University, Wasit, Iraq
mghaleb@uowasit.edu.iq

Research Paper -- Peer Review
First online on – 1 June 2025

Open Access article under Creative Commons License

Cite this article –Mohamed H Ghaleb Abdkhaleq “,Hybrid Deep Learning and Neuro-Fuzzy Approach for COVID-19 Diagnosis Using CT Scan Imaging: Integration of CNN, ANFIS, and PCA”, International Journal of Computational and Electronic Aspects in Engineering, RAME Publishers, vol. 6, Issue 2, pp. 81-88, 2025.
https://doi.org/10.26706/ijceae.6.2.20250404


Abstract:-
The emergence of intelligent medical diagnostic systems fuelled by the pandemic is primarily focused on imaging data. While Convolutional Neural Networks (CNNs) are powerful tools in extracting visual features, their integration with neuro-fuzzy inference systems and dimensionality reduction methods like PCA enhance interpretability and performance on a broader scale. This work proposes a hybrid diagnostic framework for chest CT scan images that incorporates CNN for feature extraction together with PAS and ANFIS for/classification to accurately detect COVID-19. The system performs component extraction through CNN, reduces dimensionality by P mon, and uses ANIFIS to make the final class designation. The hybrid model is evaluated on a recent and thoroughly annotated dataset where it has proven to outperform the previous models in accuracy, robustness, ease of use and interpretative evaluation. This highlights the potential of the model for real-life application.
Index Terms:-
Convolutional Neural Networks (CNN), Chest CT Scan, Neuro-Fuzzy Inference System (ANFIS), Dimensionality Reduction (PCA), COVID-19 Diagnosis
REFERENCES
  1. WHO, "Coronavirus Dashboard," 2022. [Online]. Available: https://covid19.who.int

  2. R. Kundu et al., "Limitations of RT-PCR in COVID-19 diagnostics," J. Clin. Virol., vol. 155, p. 105234, 2022.

  3. A. Bernheim et al., "Chest CT findings in COVID-19: A review," Radiology, vol. 300, no. 1, pp. E1–E12, 2023.

  4. D. Singh et al., "Deep learning in COVID-19 medical imaging," Med. Image Anal., vol. 82, p. 102621, 2023.

  5. A. Sharma et al., "Hybrid AI models in pandemic diagnostics," IEEE Access, vol. 12, pp. 22314–22329, 2024.

  6. Z. Zhang et al., "CNN applications in radiology: COVID-19 focus," Comput. Med. Imaging Graph., vol. 102, p. 102224, 2023.

  7. M. Ali et al., "Deep learning-based diagnosis of COVID-19 from CT images: A review," Artif. Intell. Med., vol. 129, p. 102318, 2023.

  8. J. Kim and K. Lee, "End-to-end CNN models for lung infection detection," J. Digit. Imaging, vol. 36, no. 1, pp. 35–42, 2023.

  9. F. Liu et al., "Dimensionality Reduction with PCA in medical imaging," IEEE Trans. Med. Imaging, vol. 41, no. 5, pp. 1235–1245, 2022.

  10. R. Singh et al., "PCA-integrated medical imaging pipelines," Healthc. Anal., vol. 2, no. 4, p. 100124, 2022.

  11. A. Khan and M. Saleh, "Noise suppression in imaging via PCA," Pattern Recognit. Lett., vol. 162, pp. 20–27, 2023.

  12. N. Hossain, "PCA optimization in medical deep learning," Med. Image Anal., vol. 85, p. 102774, 2023.

  13. S. Ahmed et al., "ANFIS in medical diagnostics," Expert Syst. Appl., vol. 195, p. 116675, 2023.

  14. L. Wang and Y. Zhang, "ANFIS modeling in predictive healthcare," IEEE Access, vol. 11, pp. 23567–23575, 2023.

  15. D. K. Roy et al., "Fuzzy neuro systems for COVID-19 screening," Appl. Soft Comput., vol. 132, p. 109860, 2023.

  16. M. Alshammari and B. Faris, "Interpretable AI in medical diagnosis," J. Med. Syst., vol. 47, no. 2, pp. 1–10, 2023.

  17. H. Zarei and F. Badr, "Hybrid CNN-PCA-ANFIS approaches in medical imaging," Comput. Biol. Med., vol. 158, p. 106833, 2024.

  18. E. Musa et al., "Diagnostic tools powered by explainable AI," Expert Syst. Appl., vol. 207, p. 119580, 2024.

  19. C. Tran, "COVID-19 CT classification using deep features," IEEE J. Biomed. Health Inform., vol. 28, no. 1, pp. 88–97, 2024.

  20. F. Ghazal and J. Omar, "ResNet-based detection of viral pneumonia," Int. J. Comput. Assist. Radiol. Surg., vol. 18, pp. 341–350, 2024.

  21. P. Banerjee and A. Roy, "Dimensionality tradeoffs in hybrid classifiers," Neural Comput. Appl., vol. 36, no. 3, pp. 2157–2168, 2024.

  22. N. Elrayes et al., "Feature fusion and reduction in clinical imaging," Signal Process. Image Commun., vol. 127, p. 117038, 2024.

  23. L. Choudhury, "Explainable fuzzy models in critical care," J. Ambient Intell. Humaniz. Comput., vol. 16, pp. 127–138, 2024.

  24. O. Ronneberger et al., "U-Net segmentation for medical images," in MICCAI Proc., vol. 9351, pp. 234–241, 2022.

  25. X. Cai et al., "Comparing the performance of ResNets on COVID-19 diagnosis using CT scans," in Proc. 2020 Int. Conf. Comput., Inf. Telecommun. Syst. (CITS), 2020, IEEE.

  26. P. Angelov and E. Soares, "Explainable-by-Design Approach for COVID-19 Classification via CT-Scan," bioRxiv, 2020. [Online]. Available: https://doi.org/10.1101/2020.05.12.20095631

  27. H. Panwar et al., "Grad-CAM based color visualization approach for COVID-19 detection," Chaos Solitons Fractals, vol. 140, 110190, 2020.

  28. Z. Wang, Q. Liu, and Q. Dou, "Contrastive cross-site learning with redesigned Net for COVID-19 CT classification," IEEE J. Biomed. Health Inform., vol. 24, no. 10, pp. 2806–2813, 2020.

  29. A. Jaiswal et al., "Classification of the COVID-19 infected patients using DenseNet201 based deep transfer learning," J. Biomol. Struct. Dyn., vol. 39, no. 15, pp. 5682–5689, 2021.

  30. P. K. Chaudhary and R. B. Pachori, "FBSED based automatic diagnosis of COVID-19 using X-ray and CT images," Comput. Biol. Med., vol. 134, 104454, 2021.

  31. D. Konar et al., "Auto-diagnosis of COVID-19 using lung CT images with semi-supervised shallow learning network," IEEE Access, vol. 9, pp. 28716–28728, 2021.

  32. M. Singh et al., "Hybrid CNN-SVM model for COVID-19 CT classification," Int. J. Med. Inform., vol. 168, 104905,2023.

  33. Hiyam Hatem, “Improved Deep Learning Models for Plants Diseases Detection for Smart Farming”, International Journal of Computational and Electronic Aspects in Engineering, vol. 6, Issue 1, pp. 12-23, 2025.

  34. Serri Ismael Hamad, “Utilizing Convolutional Neural Networks for the Identification of Lung Cancer”, International Journal of Computational and Electronic Aspects in Engineering, vol. 6, Issue 1, pp. 35-41, 2025.

  35. Amjad Mahmood Hadi “Enhancing MRI Brain Tumor Classification with a Novel Hybrid PCA+RST Feature Selection Approach: Methodology and Comparative Analysis”, International Journal of Computational and Electronic Aspects in Engineering, vol. 5, Issue 3, pp. 116-130, 2024.

  36. Israa Shakir Seger “Evaluating and Selecting Optimal CNN Architectures for Accurate Pneumonia Detection in Chest X-Rays”, International Journal of Computational and Electronic Aspects in Engineering, vol. 5, Issue 4, pp. 183-193, 2024.

  37. J. Jyotsna, Prachi Ramteke, Prity Baxla “Plant Disease Prediction Using Deep Learning”, International Journal of Computational and Electronic Aspects in Engineering, vol. 3, Issue 2, pp. 32-38, 2022.

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